Confidence: 70%
B0C16ND4L6
View on Amazon →Decision summary
Not a strong option overall. The product is materially held back by weaker formulation coherence.
Best for
Buyers comparing price and availability and okay with a middle-of-the-pack option.
Consider another option if
You care a lot about label clarity and want fewer unknowns.
Score breakdown
Tap a module to see what it measures. A 0 can reflect missing disclosure, not just a negative result.
Dosage quality
3.4/10Dosing looks weaker than ideal
Checks whether labeled ingredient amounts fall within clinically studied ranges (not just regulatory minimums). Low/0 can reflect under-dosing or missing amounts (e.g., proprietary blends).
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Dose 3.4/10 · Bioavailability 2.5/10 · Coherence 0/10
Dose quality suggests a diluted formulation.
Ingredient form quality suggests suboptimal ingredient forms.
Some ingredient forms are not declared on the label.
This is a multi-ingredient product. The score reflects formulation quality, not efficacy for a specific health goal.
Black-pepper: dose within clinically studied range (evidence B). The main limitation is that berberine: below clinically studied range.
Strengths
Weaknesses
Final verdict
Not a strong option overall. The product is materially held back by weaker formulation coherence.
A closer look at the main ingredients, how they influence the score, and the supporting evidence when available. Tap any ingredient to expand.
⚠ Strong evidence exists, but dose is below effective threshold
One of the weaker points: Dose is likely below clinically useful levels. The declared form is acceptable, but not among the best-absorbed options.
Scientific evidence
Lan et al. meta-analysis berberine and lipid profile
Journal of Ethnopharmacology • 2015
PMID: 26448206.0
Dong et al. meta-analysis berberine and glycemic control in type 2 diabetes
Metabolism • 2012
PMID: 22162995.0
✔ Dose aligned with moderate supporting evidence
One of the weaker points: Clinical dosing guidance is limited for this ingredient. The label does not specify the form, so absorption quality cannot be verified.
Scientific evidence
Rambaldi et al. Cochrane review silymarin for alcoholic or hepatitis liver disease
Cochrane Database of Systematic Reviews • 2007
PMID: 22517298.0
ℹ Dose is within established clinical ranges, but lacks direct studies
Strong contributor: Dose is strong and within effective ranges.
Clinical dosing guidance
Based on established dosing ranges used in clinical practice.
⚠ Moderate evidence exists, but dose is below effective threshold
This is a limiting factor: Dose is likely below clinically useful levels.
Scientific evidence
Hawkins et al. meta-analysis elderberry and respiratory viral infections
Complementary Medicine Research • 2016
PMID: 27023596.0
⚠ Strong evidence exists, but dose is below effective threshold
One of the weaker points: Dose is likely below clinically useful levels. The label does not specify the form, so absorption quality cannot be verified.
Scientific evidence
Wankhede et al. RCT ashwagandha and testosterone levels
American Journal of Men's Health • 2015
PMID: 31991540.0
Chandrasekhar et al. RCT ashwagandha and cortisol in stressed adults
Indian Journal of Psychological Medicine • 2012
PMID: 23439798.0
⚠ Strong evidence exists, but dose is below effective threshold
A clear drag on the formula: Dose is likely below clinically useful levels. The label does not specify the form, so absorption quality cannot be verified.
Scientific evidence
Daily et al. meta-analysis curcuminoids and joint pain
Journal of Medicinal Food • 2016
PMID: 27533649.0
Important label or formulation details that may affect how this product should be interpreted.
Berberine dose looks below clinically effective levels
Declared amount falls below ranges used in human trials.
Milk Thistle form is not clearly declared
Exact ingredient form is not disclosed on the label.
Formula design looks less coherent than stronger alternatives
The formulation appears less focused than better-built options.
Read our methodology overview to understand how SuppScoreLab combines multiple scientific dimensions into one practical score.
View methodology →This evaluation is based on the product label and declared Supplement Facts available at review time. It does not verify laboratory-tested composition, purity, or batch-level quality. This content is educational and not medical advice. Consult a qualified healthcare professional for personal health decisions. Affiliate disclosure: SuppScoreLab may earn a commission from qualifying Amazon links.
See the best Berberine supplements ranked with the same methodology, or keep exploring the database.
