EVIDENCE-BASED SUPPLEMENT SCORING
6.7/10
AVERAGE

Confidence: 80%

Optimum Nutrition Opti-Men, Vitamin C, Zinc and Vitamin D, E, B12 for Immune Support Mens Daily Multivitamin Supplement, 150 Count (Packaging May Vary)

Optimum Nutrition Opti-Men, Vitamin C, Zinc and Vitamin D, E, B12 for Immune Support Mens Daily Multivitamin Supplement (Packaging May Vary)

B00K2RJAR0

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Decision summary

CONSIDERAVERAGE

A middling option. It may be usable, but weaker formulation coherence makes better alternatives worth comparing.

Best for

Buyers comparing price and availability and okay with a middle-of-the-pack option.

Consider another option if

You prefer fully transparent formulas over blends and ambiguous labeling.

Score breakdown

Tap a module to see what it measures. A 0 can reflect missing disclosure, not just a negative result.

Dosage quality

5.0/10

Acceptable dosing, but not standout

Checks whether labeled ingredient amounts fall within clinically studied ranges (not just regulatory minimums). Low/0 can reflect under-dosing or missing amounts (e.g., proprietary blends).

Multi-ingredient formulation analysis

Dose 5/10 · Bioavailability 5.3/10 · Coherence 0/10

A proprietary blend limits independent dose verification.

This is a multi-ingredient product. The score reflects formulation quality, not efficacy for a specific health goal.

Score summary

Vitamin-d: high-bioavailability form declared (Cholecalciferol (D3)). The main limitation is that proprietary blend prevents independent dose verification.

Strengths

Vitamin-d: high-bioavailability form declared (Cholecalciferol (D3))
Iodine: dose within clinically studied range (evidence A)
Zinc: dose within clinically studied range (evidence A)

Weaknesses

Proprietary blend prevents independent dose verification
Vitamin-d: below clinically studied range
Formula coherence is weak: diluted, decorative or overly complex

Final verdict

A middling option. It may be usable, but weaker formulation coherence makes better alternatives worth comparing.

Ingredient Analysis & Evidence

A closer look at the main ingredients, how they influence the score, and the supporting evidence when available. Tap any ingredient to expand.

ℹ At the minimum effective range, but below the optimal dose; evidence is strong

Dose meets the minimum effective range, but is below the optimal dose used for stronger effects. This is a limiting factor: Dose is below the ranges usually used for stronger effects. The declared form is acceptable, but not among the best-absorbed options.

Scientific evidence

Meta-analysis

Hemila & Chalker Cochrane review vitamin C and common cold duration

Cochrane Database of Systematic Reviews • 2013

PMID: 23440782.0

RCT

Padayatty et al. RCT on vitamin C antioxidant capacity in healthy adults

Journal of the American College of Nutrition • 2001

PMID: 11684527.0

⚠ Strong evidence exists, but dose may be too low to be effective

A clear drag on the formula: Dose is likely below clinically useful levels. The declared form supports strong absorption.

Scientific evidence

Meta-analysis

Martineau et al. meta-analysis vitamin D supplementation and respiratory infections

BMJ • 2017

PMID: 26864360.0

Meta-analysis

Bischoff-Ferrari et al. meta-analysis vitamin D fracture prevention

BMJ • 2009

PMID: 20198382.0

✔ Clinically effective dose with moderate supporting evidence

Dose is within the optimal/effective range. The declared form supports strong absorption.

Scientific evidence

RCT

Broome et al. RCT selenium and immune function

American Journal of Clinical Nutrition • 2004

PMID: 14657398.0

RCT

Clark et al. RCT selenium supplementation and cancer prevention

JAMA • 1996

PMID: 8629283.0

ℹ Dose is within established clinical ranges, but lacks direct studies

Dose is within the optimal/effective range. The declared form is acceptable, but not among the best-absorbed options.

Clinical dosing guidance

Based on established dosing ranges used in clinical practice.

Min effective: 1.1 mgOptimal: 10 mgUpper: 40 mgGrade: B

ℹ Dose is within established clinical ranges, but lacks direct studies

Dose is within the optimal/effective range. A clear strength: Dose is strong and within effective ranges. The declared form is acceptable, but not among the best-absorbed options.

Clinical dosing guidance

Based on established dosing ranges used in clinical practice.

Min effective: 0.9 mgOptimal: 1.5 mgUpper: 10 mgGrade: B

✔ Clinically effective dose with strong supporting evidence

Dose is within the optimal/effective range. This is a limiting factor: Dose is strong and within effective ranges. The declared form is not one of the better-absorbed options.

Scientific evidence

Meta-analysis

Singh & Das Cochrane review zinc for common cold

Cochrane Database of Systematic Reviews • 2011

PMID: 22553186.0

RCT

Prasad et al. RCT zinc supplementation and testosterone in elderly men

Nutrition • 1996

PMID: 8875519.0

Optimum Nutrition Opti-Men, Vitamin C, Zinc and Vitamin D, E, B12 for Immune Support Mens Daily Multivitamin Supplement, 150 Count (Packaging May Vary)

Optimum Nutrition Opti-Men, Vitamin C, Zinc and Vitamin D, E, B12 for Immune Support Mens Daily Multivitamin Supplement, 150 Count (Packaging May Vary)

Warnings & notes

Important label or formulation details that may affect how this product should be interpreted.

i

Proprietary blend limits dose transparency

Exact ingredient amounts cannot be verified clearly.

Info
!

Vitamin D dose looks below clinically effective levels

Declared amount falls below ranges used in human trials.

Warning

Formula design looks less coherent than stronger alternatives

The formulation appears less focused than better-built options.

Note

Methodology

Read our methodology overview to understand how SuppScoreLab combines multiple scientific dimensions into one practical score.

View methodology →

This evaluation is based on the product label and declared Supplement Facts available at review time. It does not verify laboratory-tested composition, purity, or batch-level quality. This content is educational and not medical advice. Consult a qualified healthcare professional for personal health decisions. Affiliate disclosure: SuppScoreLab may earn a commission from qualifying Amazon links.

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