EVIDENCE-BASED SUPPLEMENT SCORING
5.6/10
AVERAGE

Confidence: 63%

Optimum Nutrition Opti-Men, Vitamin C, Zinc and Vitamin D, E, B12 for Immune Support Mens Daily Multivitamin Supplement, 150 Count (Packaging May Vary)

Optimum Nutrition Opti-Men, Vitamin C, Zinc and Vitamin D, E, B12 for Immune Support Mens Daily Multivitamin Supplement (Packaging May Vary)

B00K2RJAR0

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Decision summary

CONSIDERAVERAGE

Not a strong option overall. The product is materially held back by weaker formulation coherence.

Best for

Buyers comparing price and availability and okay with a middle-of-the-pack option.

Consider another option if

You prefer fully transparent formulas over blends and ambiguous labeling.

Score breakdown

Tap a module to see what it measures. A 0 can reflect missing disclosure, not just a negative result.

Dosage quality

4.9/10

Dosing looks weaker than ideal

Checks whether labeled ingredient amounts fall within clinically studied ranges (not just regulatory minimums). Low/0 can reflect under-dosing or missing amounts (e.g., proprietary blends).

Multi-ingredient formulation analysis

Dose 4.9/10 · Bioavailability 2.7/10 · Coherence 0/10

Dose quality suggests a diluted formulation.

Ingredient form quality suggests suboptimal ingredient forms.

A proprietary blend limits independent dose verification.

This is a multi-ingredient product. The score reflects formulation quality, not efficacy for a specific health goal.

Score summary

Vitamin-d: high-bioavailability form declared (Cholecalciferol (D3)). The main limitation is that proprietary blend prevents independent dose verification.

Strengths

Vitamin-d: high-bioavailability form declared (Cholecalciferol (D3))
Iodine: dose within clinically studied range (evidence A)
Zinc: dose within clinically studied range (evidence A)

Weaknesses

Proprietary blend prevents independent dose verification
Vitamin-d: below clinically studied range
Formula coherence is weak: diluted, decorative or overly complex

Final verdict

Not a strong option overall. The product is materially held back by weaker formulation coherence.

Ingredient Analysis & Evidence

A closer look at the main ingredients, how they influence the score, and the supporting evidence when available. Tap any ingredient to expand.

ℹ Evidence is strong, but dose is below the optimal range

This is a limiting factor: Dose is below the ranges usually used for stronger effects. The declared form is acceptable, but not among the best-absorbed options.

Scientific evidence

Meta-analysis

Hemila & Chalker Cochrane review vitamin C and common cold duration

Cochrane Database of Systematic Reviews • 2013

PMID: 23440782.0

RCT

Padayatty et al. RCT on vitamin C antioxidant capacity in healthy adults

Journal of the American College of Nutrition • 2001

PMID: 11684527.0

⚠ Strong evidence exists, but dose may be too low to be effective

A clear drag on the formula: Dose is likely below clinically useful levels. The declared form supports strong absorption.

Scientific evidence

Meta-analysis

Martineau et al. meta-analysis vitamin D supplementation and respiratory infections

BMJ • 2017

PMID: 26864360.0

Meta-analysis

Bischoff-Ferrari et al. meta-analysis vitamin D fracture prevention

BMJ • 2009

PMID: 20198382.0

ℹ Dose is below the optimal range with moderate supporting evidence

This is a limiting factor: Dose is below the ranges usually used for stronger effects. The declared form supports strong absorption.

Scientific evidence

Meta-analysis

Balk et al. systematic review chromium picolinate and glycemic control

Diabetes Technology & Therapeutics • 2007

PMID: 17519436.0

ℹ Dose is within established clinical ranges, but lacks direct studies

Adequate, but not a key strength: Dose is directionally useful, but not a standout strength.

Clinical dosing guidance

Based on established dosing ranges used in clinical practice.

Min effective: 1 mgOptimal: 5 mgUpper: 100 mgGrade: B

✔ Clinically effective dose with moderate supporting evidence

One of the weaker points: Dose is higher than typically recommended ranges. The declared form is acceptable, but not among the best-absorbed options.

Scientific evidence

RCT

Bryan et al. RCT on B vitamins and cognitive function in older adults

American Journal of Clinical Nutrition • 2002

PMID: 16920179.0

✔ Clinically effective dose with strong supporting evidence

Dose is well positioned: Dose is strong and within effective ranges.

Scientific evidence

Systematic review

Zimmermann et al. review on iodine deficiency and thyroid function in human populations

Endocrine Reviews • 2009

PMID: 19357404.0

Cohort

Bath et al. maternal iodine status and offspring cognitive outcomes (ALSPAC cohort)

Lancet • 2013

PMID: 23683674.0

Optimum Nutrition Opti-Men, Vitamin C, Zinc and Vitamin D, E, B12 for Immune Support Mens Daily Multivitamin Supplement, 150 Count (Packaging May Vary)

Optimum Nutrition Opti-Men, Vitamin C, Zinc and Vitamin D, E, B12 for Immune Support Mens Daily Multivitamin Supplement, 150 Count (Packaging May Vary)

Warnings & notes

Important label or formulation details that may affect how this product should be interpreted.

i

Proprietary blend limits dose transparency

Exact ingredient amounts cannot be verified clearly.

Info
!

Vitamin D dose looks below clinically effective levels

Declared amount falls below ranges used in human trials.

Warning

Formula design looks less coherent than stronger alternatives

The formulation appears less focused than better-built options.

Note

Methodology

Read our methodology overview to understand how SuppScoreLab combines multiple scientific dimensions into one practical score.

View methodology →

This evaluation is based on the product label and declared Supplement Facts available at review time. It does not verify laboratory-tested composition, purity, or batch-level quality. This content is educational and not medical advice. Consult a qualified healthcare professional for personal health decisions. Affiliate disclosure: SuppScoreLab may earn a commission from qualifying Amazon links.

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