EVIDENCE-BASED SUPPLEMENT SCORING
6.4/10
AVERAGE

Confidence: 90%

High Potency Berberine Supplement 500mg - Clinical Formula Berberine Capsules with Organic Cinnamon and Chromium for Internal Balance - Non-GMO Vegan & Made in US cGMP Facilities - 2 Month Supply

High Potency Berberine Supplement 500mg - Clinical Formula Berberine Capsules with Organic Cinnamon and Chromium for Internal Balance - Non-GMO Vegan & Made in US cGMP Facilities - 2 Month Supply

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Decision summary

CONSIDERAVERAGE

A middling option. It may be usable, but weaker formulation coherence makes better alternatives worth comparing.

Best for

Buyers comparing price and availability and okay with a middle-of-the-pack option.

Consider another option if

You care a lot about label clarity and want fewer unknowns.

Score breakdown

Tap a module to see what it measures. A 0 can reflect missing disclosure, not just a negative result.

Dosage quality

2.6/10

Dosing looks weaker than ideal

Checks whether labeled ingredient amounts fall within clinically studied ranges (not just regulatory minimums). Low/0 can reflect under-dosing or missing amounts (e.g., proprietary blends).

Score summary

The formula stays relatively clean on excipients. The main limitation is that chromium: below clinically studied range.

Strengths

The formula stays relatively clean on excipients
The supporting evidence profile is relatively strong
Label transparency is better than average

Weaknesses

Chromium: below clinically studied range
Formula coherence is weak: diluted, decorative or overly complex
Cinnamon: below clinically studied range

Final verdict

A middling option. It may be usable, but weaker formulation coherence makes better alternatives worth comparing.

Ingredient Analysis & Evidence

A closer look at the main ingredients, how they influence the score, and the supporting evidence when available. Tap any ingredient to expand.

ℹ Evidence is strong, but dose is below the optimal range

One of the weaker points: Dose is below the ranges usually used for stronger effects. The declared form is acceptable, but not among the best-absorbed options.

Scientific evidence

Meta-analysis

Lan et al. meta-analysis berberine and lipid profile

Journal of Ethnopharmacology • 2015

PMID: 26448206.0

Meta-analysis

Dong et al. meta-analysis berberine and glycemic control in type 2 diabetes

Metabolism • 2012

PMID: 22162995.0

⚠ Moderate evidence exists, but dose is below effective threshold

This is a limiting factor: Dose is likely below clinically useful levels. The declared form supports strong absorption.

Scientific evidence

Meta-analysis

Balk et al. systematic review chromium picolinate and glycemic control

Diabetes Technology & Therapeutics • 2007

PMID: 17519436.0

⚠ Moderate evidence exists, but dose is below effective threshold

A clear drag on the formula: Dose is likely below clinically useful levels.

Scientific evidence

Meta-analysis

Allen et al. meta-analysis cinnamon and fasting blood glucose

Journal of Medicinal Food • 2013

PMID: 22210112.0

High Potency Berberine Supplement 500mg - Clinical Formula Berberine Capsules with Organic Cinnamon and Chromium for Internal Balance - Non-GMO Vegan & Made in US cGMP Facilities - 2 Month Supply

High Potency Berberine Supplement 500mg - Clinical Formula Berberine Capsules with Organic Cinnamon and Chromium for Internal Balance - Non-GMO Vegan & Made in US cGMP Facilities - 2 Month Supply

Warnings & notes

Important label or formulation details that may affect how this product should be interpreted.

!

Chromium dose looks below clinically effective levels

Declared amount falls below ranges used in human trials.

Warning

Formula design looks less coherent than stronger alternatives

The formulation appears less focused than better-built options.

Note
!

Cinnamon dose looks below clinically effective levels

Declared amount falls below ranges used in human trials.

Warning

Methodology

Read our methodology overview to understand how SuppScoreLab combines multiple scientific dimensions into one practical score.

View methodology →

This evaluation is based on the product label and declared Supplement Facts available at review time. It does not verify laboratory-tested composition, purity, or batch-level quality. This content is educational and not medical advice. Consult a qualified healthcare professional for personal health decisions. Affiliate disclosure: SuppScoreLab may earn a commission from qualifying Amazon links.

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