EVIDENCE-BASED SUPPLEMENT SCORING
4.9/10
WEAK

Confidence: 85%

BONE SCIENCE Prime Berberine Phytosome with Berbevis and BioPerine, Metabolic Wellness Support with Ceylon Cinnamon, Banaba, Bitter Melon and Quercetin, Vegetarian Capsules

BONE SCIENCE Prime Berberine Phytosome with Berbevis and BioPerine, Metabolic Wellness Support with Ceylon Cinnamon, Banaba, Bitter Melon and Quercetin, Vegetarian Capsules

B0GMD47XK3

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Decision summary

SKIPWEAK

Not a strong option overall. The product is materially held back by weaker formulation coherence.

Best for

Only budget-focused buyers with flexible standards.

Consider another option if

You want one of the best-absorbed options in this category.

Score breakdown

Tap a module to see what it measures. A 0 can reflect missing disclosure, not just a negative result.

Dosage quality

1.7/10

Dosing looks weaker than ideal

Checks whether labeled ingredient amounts fall within clinically studied ranges (not just regulatory minimums). Low/0 can reflect under-dosing or missing amounts (e.g., proprietary blends).

Multi-ingredient formulation analysis

Dose 1.7/10 · Bioavailability 2/10 · Coherence 0/10

Dose quality suggests a diluted formulation.

Ingredient form quality suggests suboptimal ingredient forms.

This is a multi-ingredient product. The score reflects formulation quality, not efficacy for a specific health goal.

Score summary

Quercetin: high-bioavailability form declared (Quercetin Dihydrate). The main limitation is that ceylon-cinnamon: below clinically studied range.

Strengths

Quercetin: high-bioavailability form declared (Quercetin Dihydrate)

Weaknesses

Ceylon-cinnamon: below clinically studied range
Bitter-melon: below clinically studied range
Formula coherence is weak: diluted, decorative or overly complex

Final verdict

Not a strong option overall. The product is materially held back by weaker formulation coherence.

Ingredient Analysis & Evidence

A closer look at the main ingredients, how they influence the score, and the supporting evidence when available. Tap any ingredient to expand.

⚠ Limited evidence exists, and dose is below effective threshold

This is a limiting factor: Dose is likely below clinically useful levels.

Scientific evidence

Meta-analysis

Fuangchan et al. meta-analysis bitter melon and type 2 diabetes

Journal of Ethnopharmacology • 2011

PMID: 23777923.0

⚠ Dose is below commonly used clinical ranges

This is a limiting factor: Dose is likely below clinically useful levels.

Clinical dosing guidance

Based on established dosing ranges used in clinical practice.

Min effective: 1000 mgOptimal: 2000 mgUpper: 4000 mgGrade: B

ℹ Evidence is strong, but dose is below the optimal range

Adequate, but not a key strength: Dose is directionally useful, but not a standout strength. The declared form is acceptable, but not among the best-absorbed options.

Scientific evidence

Meta-analysis

Singh & Das Cochrane review zinc for common cold

Cochrane Database of Systematic Reviews • 2011

PMID: 22553186.0

RCT

Prasad et al. RCT zinc supplementation and testosterone in elderly men

Nutrition • 1996

PMID: 8875519.0

ℹ Dose is within established clinical ranges, but lacks direct studies

One of the weaker points: Dose is below the ranges usually used for stronger effects. The declared form is acceptable, but not among the best-absorbed options.

Clinical dosing guidance

Based on established dosing ranges used in clinical practice.

Min effective: 5 mgOptimal: 10 mgUpper: 20 mgGrade: B

⚠ Moderate evidence exists, but dose is below effective threshold

This is a limiting factor: Dose is likely below clinically useful levels. The declared form supports strong absorption.

Scientific evidence

Meta-analysis

Guo et al. meta-analysis quercetin and antioxidant markers

Phytotherapy Research • 2017

PMID: 27995808.0

RCT

Nieman et al. RCT quercetin and upper respiratory tract infections

Nutrients • 2007

PMID: 19965765.0

Evidence inferred from established knowledge, not directly linked studies

Adequate, but not a key strength: Clinical dosing guidance is limited for this ingredient.

No supporting studies or dosing references are currently available for this ingredient.

BONE SCIENCE Prime Berberine Phytosome with Berbevis and BioPerine, Metabolic Wellness Support with Ceylon Cinnamon, Banaba, Bitter Melon and Quercetin, Vegetarian Capsules

BONE SCIENCE Prime Berberine Phytosome with Berbevis and BioPerine, Metabolic Wellness Support with Ceylon Cinnamon, Banaba, Bitter Melon and Quercetin, Vegetarian Capsules

Warnings & notes

Important label or formulation details that may affect how this product should be interpreted.

!

Ceylon Cinnamon dose looks below clinically effective levels

Declared amount falls below ranges used in human trials.

Warning
!

Bitter Melon dose looks below clinically effective levels

Declared amount falls below ranges used in human trials.

Warning

Formula design looks less coherent than stronger alternatives

The formulation appears less focused than better-built options.

Note

Methodology

Read our methodology overview to understand how SuppScoreLab combines multiple scientific dimensions into one practical score.

View methodology →

This evaluation is based on the product label and declared Supplement Facts available at review time. It does not verify laboratory-tested composition, purity, or batch-level quality. This content is educational and not medical advice. Consult a qualified healthcare professional for personal health decisions. Affiliate disclosure: SuppScoreLab may earn a commission from qualifying Amazon links.

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