Confidence: 90%
B0DT4GFKR4
View on Amazon →Decision summary
A middling option. It may be usable, but weaker formulation coherence makes better alternatives worth comparing.
Best for
Buyers comparing price and availability and okay with a middle-of-the-pack option.
Consider another option if
You care a lot about ingredient quality and effectiveness.
Score breakdown
Tap a module to see what it measures. A 0 can reflect missing disclosure, not just a negative result.
Dosage quality
5.2/10Acceptable dosing, but not standout
Checks whether labeled ingredient amounts fall within clinically studied ranges (not just regulatory minimums). Low/0 can reflect under-dosing or missing amounts (e.g., proprietary blends).
Explore next
Dose 5.2/10 · Bioavailability 3.2/10 · Coherence 0/10
Ingredient form quality suggests suboptimal ingredient forms.
This is a multi-ingredient product. The score reflects formulation quality, not efficacy for a specific health goal.
Benfotiamine: dose within clinically studied range (evidence B). The main limitation is that berberine: below clinically studied range.
Strengths
Weaknesses
Final verdict
A middling option. It may be usable, but weaker formulation coherence makes better alternatives worth comparing.
A closer look at the main ingredients, how they influence the score, and the supporting evidence when available. Tap any ingredient to expand.
ℹ Dose is within established clinical ranges, but lacks direct studies
Dose is well positioned: Dose is strong and within effective ranges.
Clinical dosing guidance
Based on established dosing ranges used in clinical practice.
⚠ Strong evidence exists, but dose is below effective threshold
One of the weaker points: Dose is likely below clinically useful levels. The declared form is acceptable, but not among the best-absorbed options.
Scientific evidence
Lan et al. meta-analysis berberine and lipid profile
Journal of Ethnopharmacology • 2015
PMID: 26448206.0
Dong et al. meta-analysis berberine and glycemic control in type 2 diabetes
Metabolism • 2012
PMID: 22162995.0
ℹ Dose is within established clinical ranges, but lacks direct studies
Strong contributor: Dose is strong and within effective ranges.
Clinical dosing guidance
Based on established dosing ranges used in clinical practice.
ℹ Dose is below the optimal range with moderate supporting evidence
One of the weaker points: Dose is likely below clinically useful levels. The declared form is acceptable, but not among the best-absorbed options.
Scientific evidence
Bryan et al. RCT on B vitamins and cognitive function in older adults
American Journal of Clinical Nutrition • 2002
PMID: 16920179.0
ℹ Dose is below the optimal range with moderate supporting evidence
One of the weaker points: Dose is likely below clinically useful levels. The declared form is acceptable, but not among the best-absorbed options.
Scientific evidence
Clarke et al. meta-analysis B vitamins and cognitive decline
American Journal of Clinical Nutrition • 2007
PMID: 22243457.0
Shipton & Thachil review of vitamin B12 deficiency and fatigue
Postgraduate Medical Journal • 2015
PMID: 20648714.0
Evidence inferred from established knowledge, not directly linked studies
Supports the formula, but not a major driver: Clinical dosing guidance is limited for this ingredient.
No supporting studies or dosing references are currently available for this ingredient.
Important label or formulation details that may affect how this product should be interpreted.
Berberine dose looks below clinically effective levels
Declared amount falls below ranges used in human trials.
Formula design looks less coherent than stronger alternatives
The formulation appears less focused than better-built options.
Vitamin B6 dose looks below clinically effective levels
Declared amount falls below ranges used in human trials.
Read our methodology overview to understand how SuppScoreLab combines multiple scientific dimensions into one practical score.
View methodology →This evaluation is based on the product label and declared Supplement Facts available at review time. It does not verify laboratory-tested composition, purity, or batch-level quality. This content is educational and not medical advice. Consult a qualified healthcare professional for personal health decisions. Affiliate disclosure: SuppScoreLab may earn a commission from qualifying Amazon links.
See the best Berberine supplements ranked with the same methodology, or keep exploring the database.
